×
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
Malignant neoplasm of lung
0.400
Biomarker
BEFREE
⁵¹Cr release assay, CD107a assay, and IFN-γ secretion assay were performed to detect the sensitivity of lung cancer cell lines A549 and H1975 to NK cells cytotoxicity in the presence of gefitinib.
23937717 2013
×
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Malignant neoplasm of lung
0.100
Biomarker
BEFREE
• Bone marrow FDG uptake can provide information on predicting lung cancer progression.
27590191 2017
×
Entrez Id: 114757
Gene Symbol: CYGB
CYGB
Malignant neoplasm of lung
0.030
Biomarker
BEFREE
ΔNp63 targets cytoglobin to inhibit oxidative stress-induced apoptosis in keratinocytes and lung cancer .
26096935 2016
×
Entrez Id: 3014
Gene Symbol: H2AX
H2AX
Malignant neoplasm of lung
0.070
AlteredExpression
BEFREE
γ-H2AX activity as shown by measuring DSB damage in ionizing radiation-irradiated PBLs may be a novel phenotypic marker of lung cancer risk.
23300022 2013
×
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Malignant neoplasm of lung
0.100
Biomarker
BEFREE
β-Elemene Synergizes With Gefitinib to Inhibit Stem-Like Phenotypes and Progression of Lung Cancer via Down-Regulating EZH2 .
30555330 2018
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of lung
0.800
AlteredExpression
BEFREE
β-Elemene against human lung cancer via up-regulation of P53 protein expression to promote the release of exosome.
25204604 2014
×
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4
Malignant neoplasm of lung
0.100
Biomarker
BEFREE
α7-nAChR silencing inhibits lung cancer proliferation.
25324001 2014
×
Entrez Id: 407041
Gene Symbol: MIR34B
MIR34B
Malignant neoplasm of lung
0.360
Biomarker
CTD_human
α4 is highly expressed in carcinogen-transformed human cells and primary human cancers.
21339737 2011
×
Entrez Id: 3476
Gene Symbol: IGBP1
IGBP1
Malignant neoplasm of lung
0.300
Biomarker
CTD_human
α4 is highly expressed in carcinogen-transformed human cells and primary human cancers.
21339737 2011
×
Entrez Id: 100
Gene Symbol: ADA
ADA
Malignant neoplasm of lung
0.330
Biomarker
CTD_human
[Increase of the functional activity of natural killers under the effects of the pharmacological correction of the sympathoadrenal system state in patients with lung cancer].
2305558 1990
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of lung
0.800
Therapeutic
CTD_human
[Experimental study on combination of Ad-p53 with CDDP or As(2)O(3) in human lung adenocarcinoma cell line GLC-82].
11798837 2000
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of lung
0.800
Biomarker
CTD_human
[Experimental study on combination of Ad-p53 with CDDP or As(2)O(3) in human lung adenocarcinoma cell line GLC-82].
11798837 2000
×
Entrez Id: 4233
Gene Symbol: MET
MET
Malignant neoplasm of lung
0.400
Biomarker
BEFREE
[Corrigendum] AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis.
30542697 2019
×
Entrez Id: 558
Gene Symbol: AXL
AXL
Malignant neoplasm of lung
0.100
Biomarker
BEFREE
[Corrigendum] AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis.
30542697 2019
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
[K-ras gene mutations of asbestos and welding-fumes related human lung cancer ].
12725029 2000
×
Entrez Id: 7545
Gene Symbol: ZIC1
ZIC1
Malignant neoplasm of lung
0.010
AlteredExpression
BEFREE
ZIC1 knockdown inhibits proliferation, reduces invasion, and induces apoptosis in dedifferentiated and myxoid/round cell liposarcoma cell lines, but not in either adipose-derived stem cells or in a lung cancer cell line with low ZIC1 expression.
20713527 2010
×
Entrez Id: 4017
Gene Symbol: LOXL2
LOXL2
Malignant neoplasm of lung
0.020
Biomarker
BEFREE
ZEB1 induces LOXL2 -mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis.
27694892 2017
×
Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8
Malignant neoplasm of lung
0.100
Biomarker
BEFREE
ZCCHC9 promotes proliferation and invasion of lung cancer through regulating the JNK pathway.
30644129 2019
×
Entrez Id: 5226
Gene Symbol: PGD
PGD
Malignant neoplasm of lung
0.020
AlteredExpression
BEFREE
YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation.
31504235 2019
×
Entrez Id: 406924
Gene Symbol: MIR134
MIR134
Malignant neoplasm of lung
0.030
Biomarker
BEFREE
YKT6 is a key molecule in the regulation of exosome release in lung cancer cells and is in turn precisely regulated by miR-134 and miR-135b.
27285987 2016
×
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Malignant neoplasm of lung
0.100
Biomarker
BEFREE
YHO-13177 potentiated the cytotoxicity of SN-38, mitoxantrone, and topotecan in both BCRP -transduced human colon cancer HCT116 (HCT116/BCRP) cells and SN-38-resistant human lung cancer A549 (A549/SN4) cells that express BCRP , but had little effect in the parental cells.
21566063 2011
×
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
Malignant neoplasm of lung
0.400
Biomarker
BEFREE
Yet only in Asian populations, both Japanese and Chinese, which have a high prevalence of genetic variants, has a link between CYP2A6 , smoking dose, and lung cancer been established.
28092945 2017
×
Entrez Id: 494324
Gene Symbol: MIR375
MIR375
Malignant neoplasm of lung
0.040
Biomarker
BEFREE
YAP1 showed a negative correlation with miR-375 in a panel of lung cancer cell lines and growth inhibitory activities in NE-lung cancer cells.
21856745 2011
×
Entrez Id: 5591
Gene Symbol: PRKDC
PRKDC
Malignant neoplasm of lung
0.030
GeneticVariation
BEFREE
XRCC6 and XRCC7 with susceptibility and survival in North Indian lung cancer patients.
29397516 2018
×
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
Malignant neoplasm of lung
0.400
Biomarker
BEFREE
XRCC1 is an important scaffold protein involved in base excision repair that is regulated by ERK1 /2 and AKT signals and plays an important role in the development of lung cancer .
26046675 2015